ICSI- Intracytoplasmic Sperm Injection

Intracytoplasmic Sperm Injection is a micromanipulation that implies injection of a single sperm directly into the  egg cytoplasm   by the embryologist.  During  the standard IVF the egg   and the sperm placed in a culture dish  merge spontaneously.  

Indications for ICSI are:

  • Low oocyte fertilization percentage during previous cycles.  Though sometimes, despite the normal findings  sperm can not  penetrate the egg.  In this case problems of genetic and immunological  character, or idiopathic infertility  are likely.
  • Abnormal  findings on spermogram : low spermatozoid concentration and their abnormal  morphology and  motility  determines the necessity of ICSI micromanipulation. ICSI is required   in case of  low spermatozoid concentration   and  in a number of cases  when  despite the high concentration  of spermatozoids they are not able to   penetrate the transparent membrane  surrounding the oocyte if their motility and morphology is not normal.   
  • Oligospermia and Azoospermia: Azoospermia is a pathological condition when the number of spermatozoids in  the man’s ejaculate  are extremely low.

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