ICSI- Intracytoplasmic Sperm Injection
Intracytoplasmic Sperm Injection is a micromanipulation that implies injection of a single sperm directly into the egg cytoplasm by the embryologist. During the standard IVF the egg and the sperm placed in a culture dish merge spontaneously.
Indications for ICSI are:
- Low oocyte fertilization percentage during previous cycles. Though sometimes, despite the normal findings sperm can not penetrate the egg. In this case problems of genetic and immunological character, or idiopathic infertility are likely.
- Abnormal findings on spermogram : low spermatozoid concentration and their abnormal morphology and motility determines the necessity of ICSI micromanipulation. ICSI is required in case of low spermatozoid concentration and in a number of cases when despite the high concentration of spermatozoids they are not able to penetrate the transparent membrane surrounding the oocyte if their motility and morphology is not normal.
- Oligospermia and Azoospermia: Azoospermia is a pathological condition when the number of spermatozoids in the man’s ejaculate are extremely low.